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retatrutide glp-1 gip glucagon receptor agonist Treatment with retatrutide, an agonist to GLP-1, GIP, and glucagon receptors in one molecule, was associated with unprecedented drops in weight from people with or without type 2 diabetes in a pair

Marsoni M251S
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4.1 ★★★★★
Based on 969 reviews
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Noelle
Pawtucket, US
★★★★★ 5
Helped Tighten My Skin & Minimize Pores
Color: Cyano Pink Spicule, Color: Cyano Pink Spicule
I’ve loved the Dr. Melaxin Cyano Pink Spicule Serum! The bottle is small, but it lasted me around 6 months since I only use one pump every other night. When I first started using it, I noticed a tingling sensation, but over time my skin adjusted and I barely notice it now. I’ve definitely seen my pores appear smaller and my skin feels tighter and smoother after using it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 26, 2026
B
Verified Purchase
Brooke Ballinger
Phoenix, US
★★★★★ 5
Great for pore reduction
Color: Cyano Pink Spicule
This product works great!! it almost feels like an exfoliator. It reduced the pours on my nose, which were very big and now you can barely see them. I would recommend this product if you have large pores also make skin look firmer and smoother more for a night cream though.
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Reviewed in the United States on May 31, 2026
M
Verified Purchase
Marcia Weldon
Phoenix, US
★★★★★ 5
More than expected
Color: Cyano Pink Spicule
Love, love and recommended to friends. Leaves my skin feeling and looking great. At 69 I don't expect miracles but can definitely see an improvement in texture, glow and line minimizing. I'm hooked and will never be without!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 5, 2026
E
Verified Purchase
Eric S.
San Leandro, US
★★★★★ 5
Micro-needling effect!
Color: Cyano Pink Spicule
Love how you can feel the micro-needling effect. I use this is my first application after toning and follow up with my serum and moisturizing routine. I do believe it gives my face a plump feeling, especially after gua sha. Will continue to use in my daily!
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Reviewed in the United States on May 21, 2026
M
Verified Purchase
Michelle B. Govertsen
Waukegan, US
★★★★★ 4
Helps my moisturizer absorb better
Color: Cyano Pink Spicule
I’m not quite sure if the product is fully working the way it is supposed to but I do like that when I use this and the apply moisturizer, it absorbs into my skin better and leaves my skin smoother and a lot less greasy. It’s easy to throw in my travel bag because of the size and you really only just need a little for each use so it goes a long way got the cost.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 31, 2026

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